AME 589/489

Engineering Properties and Micro/Nano Technologies for Biological Systems

 

Jointly taught by: Dr. Eniko T. Enikov , Aerospace and Mechanical Engineering; 621-4506, enikov@engr.arizona.edu 

Dr. Joel L. Cuello, Agricultural and Biosystems Engineering; 621-7757, jcuello@ag.arizona.edu

 

Lectures:              T,Th 2:00 – 2:50 P.M.           S Sci 132 (this location might change)

Lab sessions:       Fri 2:00-4.50pm                      AME 420S or Clean Room in ECE Annex Building (1st half of class); PAS 132 (2nd half of class)

                               

Catalogue Data:  This course tackles the structures and physical properties -- including mechanical, thermodynamic, electrical, etc. -- of biological materials -- including human, animal, plant and food materials -- that are necessary in the engineering analysis, evaluation, synthesis and design of biological systems. It then combines this knowledge with the techniques for the design, assembly and manufacturing of conventional microelectromechanical systems (MEMs) and nanodevices and applies them to biological systems.

 

Texts:                     Introduction of Mircroelectronic Fabrication, Richard  C. Jaeger, Prentice Hall,  2002,

Additional Suggested Texts:

 

Gardner, J.W. 1994. Microsensors, Principles and Applications. John Willey & Sons

Class notes will be integral part of instruction. Material presented in class will supplement and will sometimes be different from the textbooks.

 

Exams:                   September: Midterm Exam #1 (ca. 9/19, exact date TBA)

October: Midterm Exam #2 (ca. 10/12, exact date TBA)

November: Midterm Exam #3 (ca. 11/9, exact date TBA)

December: Midterm Exam #4 (ca. 11/30, exact date TBA)

 

December: Final Exam exact (date TBA)

 

Grading:                                                                                                                Undergraduate                     Graduate

 

                                                Exams (4)                                                               50%                                        50%

                                                Homeworks, Labs, Quizzes                                 20%                                        10%

                                                Design Reports (1)                                               15%                                        25%

                                                Final Exam                                                             15%                                        15%

 

Design Project:   Click here for sample for MEMS (part #2  of class )

 

Topics:                                  

Week 1   Introduction to MEMs and NEMs, Transducers: classification and characteristics

Lab1       Introduction of pressure sensor project

Week 2   Working Principles of Microsystems; Scaling Laws in Miniaturization.

Lab 2      Photomask Design Exercise: ACAD

Week 3   Analysis of Common MEMS structures: Plates , Breams, and Cantilevers. Nano- and Pico-Newton Force Measurement with MEMS.

Lab 3      Design of pressure sensor structures: sensitivity, resolution, expected noise levels

Week 4  Biosensors: Amperometric, Potentiometric, Micro-PCR, Whole-cell biosensors.

Lab 4      Photolithography experiment.

Week 5  Exam 1. Microsystems Design and Fabrication: Substrates and Materials.

Lab 5      Si oxidation and BOE etching experiment.

Week 6   Photolithography. Oxidation. Wet and Dry Etching

Lab 6      Anisotropic etching experiment.

Week 7   Wet and Dry Etching  Doping via Diffusion and Ion-Implantation. Vacuum Deposition of Metals

Lab7       Sensor wiring and testing

Week 8   Vacuum Deposition of Metals. Exam 2

Lab8:      Project report preparation.  Please turn in the following week.

 

Part 2

Week 9                   Biology-Inspired Materials

Week 10                 Deformation of Biological Solids, Thermal Properties, Viscoelasticity and Rheology

Week 11                 Viscosity and Flow of Biological Liquids and Semisolids

Week 12                 Biosensors and Performance Factors. Exam 3

Lab 10                    Designing a Biosensor

Week 13                 Biological Elements

Week 14                 Transducers

Week 15                 Applications. Exam 4

Week 16                 Project Presentations