Research Expertise
| • | Single Molecule Detection and Manipulation |
| • | Molecular and Cellular Biomechanics |
| • | BioMEMS, Micro- and Nanofluidics |
| • | Computational Systems Biology |
| • | Point-of-care diagnostic |
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Education
| • | Ph.D. | : | Mechanical and Aerospace Engineering, University of California, Los Angeles, 2005 |
| • | M.S. | : | Mechanical and Aerospace Engineering, University of California, Los Angeles, 2001 |
| • | B.E. | : | Mechanical and Automation Engineering, The Chinese University of Hong Kong, 1999 |
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Courses Taught (since 2006)
| • | AME 300 | : | Laboratory Instrumentation |
| • | AME 413b | : | Mechanical Engineering Design Lab [supervised project] |
| • | AME 4/588 | : | Micro and Nano Transducer Physics and Design |
| • | ENGR 498a/b | : | Cross-Disciplinary Design [supervised project] |
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Employment
| • | 8/06-date | : | Aerospace and Mechanical Engineering, The University of Arizona: Assistant Professor |
| • | 8/06-date | : | BIO5 Institute, The University of Arizona: Assistant Professor |
| • | 05/05-8/06 | : | Institute of Cell Mimetic Space Exploration, UCLA: Postdoctoral Research Associate |
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Honors and Awards
| • | Foreign Travel Grant, International Affairs, University of Arizona, 2007 |
| • | Saint Paul Foundation Scholarship, UCLA, 2002 |
| • | Chung Chi College Creative Design Awards, CUHK, 1999 |
| • | Dr. Lu Chung-Lun Memorial Scholarship, CUHK, 1998 |
| • | Chung Chi College Academic Awards, CUHK, 1996, 1997, 1998 |
| • | Joyce M. Kuok Foundation Scholarships, CUHK, 1996, 1997 |
| • | National Christian University Scholarship, CUHK, 1996 |
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Professional Societies
| • | APS | : | American Physical Society |
| • | BMES | : | Biomedical Engineering Society |
| • | IEEE | : | Institute of Electrical and Electronics Engineers |
| • | --- | : | Society for Biomaterials |
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Publications (since 2004)
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D.-H. Kim, P. K. Wong, J. Park, A. Levchenko, and Y. Sun, "Microengineered Platforms for Cell Mechanobiology," Annual Review of Biomedical Engineering (in press). |
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M. Junkin, J. Watson, J. P. Vande Geest, and Wong, P.K., "Template-guided self-assembly of colloidal quantum dots using plasma lithography", Advanced Materials (in press). |
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A. Lau, N. F. Villeneuve, Z. Sun, P. K. Wong, D. D. Zhang, "Dual roles of Nrf2 in cancer", Pharmacological Research (in press). |
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J. Keyes, M. Junkin, J. Cappello, X. Wu, and P. K. Wong, "Evaporation-induced assembly of biomimetic polypeptides," Appl. Phys. Lett. 93, 023120, 2008. DOI:10.1063/1.2957992 (This paper is selected for publication in the Virtual Journal of Nanoscale Science & Technology and in the Virtual Journal of Biological Physics Research) |
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P. K. Wong, F. Yu, A. Shahangian, G. Cheng, R. Sun, and C.-M. Ho, "Closed-Loop Control of Cellular Functions using a Stochastic Search Algorithm," Proceedings of the National Academy of Sciences 105, 5105-5110, 2008. DOI: 10.1073/pnas.0800823105 (This paper is featured in over 50 news highlights including Eureka, Science Daily) |
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D. Meserve, Z. Wang, D. D. Zhang, and P. K. Wong, "A double-stranded molecular probe for homogeneous nucleic acid analysis," Analyst 133, 1313-1319, 2008. DOI: 10.1039/b804853c. (This paper is selected for publication in the RSC's Chemical Biology Research Article Virtual Journal) |
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X. J. Wang, Z. Sun, N. F. Villeneuve, S. Zhang, F. Zhao, Y. Li, W. Chen, X. Yi, W. Zheng, G. T. Wondrak, P. K. Wong, and D. D. Zhang, "Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2," Carcinogenesis 29, 1235-1243, 2008. DOI: 10.1093/carcin/bgn095 |
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Z. Wang, V. Gidwani, D. D. Zhang and P. K. Wong, "Separation-free detection of nuclear factor kappa B with double-stranded molecular probes", Analyst 133, 998-1000, 2008. DOI: 10.1039/b809113g (Cover article) (This paper is selected for publication in the RSC's Chemical Biology Research Article Virtual Journal) |
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Y. Du, N. F. Villeneuve, X. Wang, Z. Sun, W. L. Chen, J., H. Lou, P. K. Wong, and D. D. Zhang, "Oridonin confers protection against arsenic induced toxicity through activation of the Nrf2-mediated defensive response," Environmental Health Perspectives 2008. DOI: 10.1289/ehp.11464 |
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Z. Wang, V. Gidwani, Z. Sun, D. D. Zhang, and P. K. Wong, "Development of a molecular assay for rapid screening of chemopreventive compounds targeting Nrf2," Journal of the Association for Laboratory Automation 13, 243-248, 2008. DOI: 10.1016/j.jala.2008.03.007 |
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P. K. Wong and D. Ho, "Emergent Diagnostic and Therapeutic Platforms for Nanoengineered Medicine," IEEE Nanotechnology Magazine 2, 9-13, 2008. DOI: 10.1109/MNANO.2008.920054 |
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Pak Kin Wong, Winny Tan, Chih-Ming Ho, "Cell Relaxation after Electrodeformation: Effect of Latrunculin A on Actin Cytoskeleton", Journal of Biomechanics 38, 529-535, 2005. |
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Tza-Huei Wang, Yahui Peng, Chunyang Zhang, Pak Kin Wong, Chih-Ming Ho, "Single-Molecule Tracing on a Fluidic Microchip for Quantitative Detection of Low-Abundance Nucleic Acids", Journal of American Chemical Society 127, 5354-5359, 2005. (Highlighted in Nanozone news in Nature, April 28, 2005) |
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Pak Kin Wong, Che-Yang Chan, Tza-Huei Wang and Chih-Ming Ho "Electrokinetic Bioprocessor for Concentrating Cells and Molecules", Analytical Chemistry 76, 6908-6914, 2004. (This work has been highlighted in NIH NIDCR website) |
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Pak Kin Wong, Tza-Huei Wang, Joanne H. Deval, Chih-Ming Ho, "Electrokinetics in Micro Devices for Biotechnology Applications", IEEE/ASME Transactions on Mechatronics 9, 366-376, 2004. |
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Pak Kin Wong, Umberto Ulmanella and Chih-Ming Ho, "Fabrication of Microsurgical Tools for Single Cell Intracytoplasmic Injection", Journal of Microelectromechanical System 6, 940-946, 2004. |
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Research Grants (since 2006)
| • | Molecular Probe Biosensors for Rapid Screening of Photoprotective Compounds, Arizona Biomedical Research Commission, 07/1/08-06/30/11 |
| • | A Nrf2 Bioassay for Screening of Cancer Chemopreventive Compounds, Prevent Cancer Foundation, 07/15/08-07/14/10 |
| • | Diffusion of Structured Polymers in Confined Environments, American Chemical Society, 01/01/08-08/31/10 |
| • | Molecular Probe Biosensors for Rapid Screening of Chemopreventive Compounds, American Cancer Society IRG AZCC, 07/01/08-06/30/09 |
| • | Development of electrokinetic/microfluidic devices for studying chromatin structure, Center for Insect Science University of Arizona, 07/01/08-06/30/09 |
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A Rapid Microfluidic Assay for High-Throughput Screening of Chemopreventive Compounds, Johns Hopkins Center for Alternatives to Animal Testing, 02/01/08-01/31/09 |
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